ABSTRACT
[This retracts the article DOI: 10.1007/s10639-021-10588-y.].
ABSTRACT
Background: This study aims to describe COVID-19–related clinical outcomes after immunotherapies (ICIs) for cancer patients. Methods: In this meta-analysis, we searched databases to collect data that addressed outcomes after immunotherapies (ICIs) during the COVID-19 pandemic. The primary endpoint was COVID-19–related mortality. Secondary endpoints included COVID-related hospital readmission, emergency room (ER) visits, opportunistic infections, respiratory complications, need for ventilation, and thrombo-embolic events. Pooled event rates (PERs) were calculated and a meta-regression analysis was performed. Results: A total of 262 studies were identified. Twenty-two studies with a total of forty-four patients were eligible. The PER of COVID-19–related mortality was 39.73%, while PERs of COVID-19–related ER visits, COVID-19–related pulmonary complications, and COVID-19–related ventilator needs were 40.75%, 40.41%, and 34.92%, respectively. The PER of opportunistic infections was 34.92%. The PERs of the use of antivirals, antibiotics, steroids, prophylactic anticoagulants, and convalescent plasma were 62.12%, 57.12%, 51.36%, 41.90%, and 26.48%, respectively. There was a trend toward an association between previous respiratory diseases and COVID-19–related mortality. Conclusion: The rates of COVID-19–related mortality, ER visits, pulmonary complications, need for a ventilator, and opportunistic infections are still high after ICIs during the COVID-19 pandemic. There was a trend toward an association between previous respiratory diseases and COVID-19–related mortality.
ABSTRACT
We conducted this meta-analysis to address the outcomes in cancer patients after oncologic surgery during COVID-19 pandemic. The primary endpoint was the COVID-19-related mortality rate. Higher body mass index was significantly and negatively associated with higher all-cause mortality and in-hospital COVID-19 infection rates. Male sex, preoperative respiratory disease, and smoking history were positively and significantly associated with increased all-cause mortality rates. Furthermore, male sex was positively and significantly associated with the COVID-19 infection rate.
Subject(s)
COVID-19 , Neoplasms , COVID-19/complications , Humans , Male , Medical Oncology , Neoplasms/complications , Neoplasms/mortality , Pandemics , Risk Factors , SARS-CoV-2 , Sex Factors , Smoking/adverse effectsABSTRACT
These days, distance learning has almost completely replaced traditional teaching methods due to the COVID-19 pandemic and the introduction of quarantine measures. A sharp rise in interest in distance learning methodology has raised a number of new questions and challenges. This research examines changes in the training process and cognitive abilities and academic performance during the coronavirus pandemic. Students of the I.M. Sechenov University and Al Ain University were surveyed (103) during classroom and distance English learning before and during the COVID-19. Three samples of the average values of the respondents' self-assessment of academic performance, cognitive abilities (namely concentration and memory), progress in performing oral assignments, progress in performing written assignments, ability to absorb information while reading and by ear; general health condition during the training and were obtained and tested for the Gaussian distribution law compliance. All of the rates studied fell during distance learning during a pandemic compared to distance learning outside a pandemic. However, it should be noted that they still turned out to be higher than the marks obtained in classroom teaching. Students were interviewed for possible factors influencing the reviewed teaching modes effectiveness (the survey showed that these factors are an increase in the amount of leisure time, ability to take breaks more often, more comfortable learning environment, no need to spend time on the road to the university).